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      2-D Minimum Variance Based Plane Wave Compounding with Generalized Coherence Factor in Ultrafast Ultrasound Imaging

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          Abstract

          Plane wave compounding (PWC) is an effective modality for ultrafast ultrasound imaging. It can provide higher resolution and better noise reduction than plane wave imaging (PWI). In this paper, a novel beamformer integrating the two-dimensional (2-D) minimum variance (MV) with the generalized coherence factor (GCF) is proposed to maintain the high resolution and contrast along with a high frame rate for PWC. To specify, MV beamforming is adopted in both the transmitting aperture and the receiving one. The subarray technique is therefore upgraded into the sub-matrix division. Then, the output of each submatrix is used to adaptively compute the GCF using a 2-D fast Fourier transform (FFT). After the 2-D MV beamforming and the 2-D GCF weighting, the final output can be obtained. Results of simulations, phantom experiments, and in vivo studies confirm the advantages of the proposed method. Compared with the delay-and-sum (DAS) beamformer, the full width at half maximum (FWHM) is 90% smaller and the contrast ratio (CR) improvement is 154% in simulations. The over-suppression of desired signals, which is a typical drawback of the coherence factor (CF), can be effectively avoided. The robustness against sound velocity errors is also enhanced.

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          High-resolution frequency-wavenumber spectrum analysis

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            Coherent plane-wave compounding for very high frame rate ultrasonography and transient elastography.

            The emergence of ultrafast frame rates in ultrasonic imaging has been recently made possible by the development of new imaging modalities such as transient elastography. Data acquisition rates reaching more than thousands of images per second enable the real-time visualization of shear mechanical waves propagating in biological tissues, which convey information about local viscoelastic properties of tissues. The first proposed approach for reaching such ultrafast frame rates consists of transmitting plane waves into the medium. However, because the beamforming process is then restricted to the receive mode, the echographic images obtained in the ultrafast mode suffer from a low quality in terms of resolution and contrast and affect the robustness of the transient elastography mode. It is here proposed to improve the beamforming process by using a coherent recombination of compounded plane-wave transmissions to recover high-quality echographic images without degrading the high frame rate capabilities. A theoretical model is derived for the comparison between the proposed method and the conventional B-mode imaging in terms of contrast, signal-to-noise ratio, and resolution. Our model predicts that a significantly smaller number of insonifications, 10 times lower, is sufficient to reach an image quality comparable to conventional B-mode. Theoretical predictions are confirmed by in vitro experiments performed in tissue-mimicking phantoms. Such results raise the appeal of coherent compounds for use with standard imaging modes such as B-mode or color flow. Moreover, in the context of transient elastography, ultrafast frame rates can be preserved while increasing the image quality compared with flat insonifications. Improvements on the transient elastography mode are presented and discussed.
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              Effect of skin impedance on image quality and variability in electrical impedance tomography: a model study.

              A computer simulation is used to investigate the relationship between skin impedance and image artefacts in electrical impedance tomography. Sets of electrode impedance are generated with a pseudo-random distribution and used to introduce errors in boundary voltage measurements. To simplify the analysis, the non-idealities in the current injection circuit are replaced by a fixed common-mode error term. The boundary voltages are reconstructed into images and inspected. Where the simulated skin impedance remains constant between measurements, large impedances (> 2k omega) do not cause significant degradation of the image. Where the skin impedances 'drift' between measurements, a drift of 5% from a starting impedance of 100 omega is sufficient to cause significant image distortion. If the skin impedances vary randomly between measurements, they have to be less than 10 omega to allow satisfactory images. Skin impedances are typically 100-200 omega at 50 kHz on unprepared skin. These values are sufficient to cause image distortion if they drift over time. It is concluded that the patient's skin should be abraded to reduce impedance, and measurements should be avoided in the first 10 min after electrode placement.
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                Author and article information

                Journal
                Sensors (Basel)
                Sensors (Basel)
                sensors
                Sensors (Basel, Switzerland)
                MDPI
                1424-8220
                23 November 2018
                December 2018
                : 18
                : 12
                : 4099
                Affiliations
                [1 ]Department of Electronic Engineering, Fudan University, Shanghai 200433, China; 17110720012@ 123456fudan.edu.cn (Y.Q.); jhyu@ 123456fudan.edu.cn (J.Y.); guoyi@ 123456fudan.edu.cn (Y.G.)
                [2 ]Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention (MICCAI) of Shanghai, Shanghai 200032, China
                Author notes
                [* ]Correspondence: yywang@ 123456fudan.edu.cn
                Author information
                https://orcid.org/0000-0003-2591-8339
                Article
                sensors-18-04099
                10.3390/s18124099
                6308455
                30477114
                fec0b0f6-52d3-4a87-a1af-d3c3ea8189fe
                © 2018 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 28 October 2018
                : 21 November 2018
                Categories
                Article

                Biomedical engineering
                ultrafast ultrasound imaging,transducer arrays,plane wave compounding,adaptive beamforming,minimum variance,generalized coherence factor

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