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      Polypeptide Fraction from Bovine Factor VIII Used in Fluorangiography

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          Abstract

          We report a new method of fluorangiography employing a polypeptide fraction from bovine factor VIII that has shown remarkable affinity to the endothelial surface of microvessels. Rabbits injected with this compound, labeled with fluorescein isothiocyanate, show a very delayed dissappearance time of fluorescence in retinal vessels when compared with those injected with ordinary fluorescein. This allows a good observation of the late time, which is of great diagnostic advantage for several pathological conditions.

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          Author and article information

          Journal
          OPH
          Ophthalmologica
          10.1159/issn.0030-3755
          Ophthalmologica
          S. Karger AG
          0030-3755
          1423-0267
          1988
          1988
          31 March 2010
          : 197
          : 1
          : 51-55
          Affiliations
          aOphthalmological Clinic University of Pisa; bBaldacci Research Laboratories, Pisa, Italy
          Article
          309918 Ophthalmologica 1988;197:51–55
          10.1159/000309918
          3141864
          © 1988 S. Karger AG, Basel

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          Page count
          Pages: 5
          Categories
          Original Paper

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