Suguru Hayase 1 , Yoshihito Sasaki , Tsutomu Matsubara , Daekwan Seo , Masaaki Miyakoshi , Tsubasa Murata , Takashi Ozaki , Kennichi Kakudo , Kensuke Kumamoto , Kris Ylaya , Sheue-yann Cheng , Snorri S Thorgeirsson , Stephen M Hewitt , Jerrold M Ward , Shioko Kimura
Mouse thyroid side population (SP) cells consist of a minor population of mouse thyroid cells that may have multipotent thyroid stem cell characteristics. However the nature of thyroid SP cells remains elusive, particularly in relation to thyroid cancer. Stanniocalcin (STC) 1 and 2 are secreted glycoproteins known to regulate serum calcium and phosphate homeostasis. In recent years, the relationship of STC1/2 expression to cancer has been described in various tissues.