Expression of stanniocalcin 1 in thyroid side population cells and thyroid cancer cells.

Abstract

Mouse thyroid side population (SP) cells consist of a minor population of mouse thyroid cells that may have multipotent thyroid stem cell characteristics. However the nature of thyroid SP cells remains elusive, particularly in relation to thyroid cancer. Stanniocalcin (STC) 1 and 2 are secreted glycoproteins known to regulate serum calcium and phosphate homeostasis. In recent years, the relationship of STC1/2 expression to cancer has been described in various tissues.

Journal

Journal ID (iso-abbrev): Thyroid

Title: Thyroid : official journal of the American Thyroid Association

Publisher: Mary Ann Liebert Inc

ISSN (Electronic): 1557-9077

ISSN (Print): 1050-7256

Publication date (Electronic): Apr 2015

Volume: 25

Issue: 4

Affiliations

[1 ] 1 Laboratory of Metabolism, National Cancer Institute, National Institutes of Health , Bethesda, Maryland.

Article

DOI: 10.1089/thy.2014.0464

PMC ID: 4390205

PubMed ID: 25647164