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Early cellular and stromal responses in regeneration versus repair of a mammalian bladder using autologous cell and biodegradable scaffold technologies.

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      Abstract

      Internal organ regeneration holds promise for changing medical technology and decreasing organ shortages. Current medical treatment for internal organ failure is largely limited to organ transplantation. A construct composed of synthetic biopolymer with autologous cells has shown long-term clinical benefit in patients undergoing augmentation cystoplasty. However, to our knowledge early cellular and stromal events during bladder regeneration have not been elucidated.

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      Affiliations
      [1 ] Tengion, Inc., Winston-Salem, North Carolina 27103, USA.
      Journal
      J. Urol.
      The Journal of urology
      Elsevier BV
      1527-3792
      0022-5347
      Jul 2008
      : 180
      : 1
      18499157
      S0022-5347(08)00532-6
      10.1016/j.juro.2008.02.039

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