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      Laparoscopic cholecystectomy with common bile duct exploration for choledocholithiasis in a patient with situs inversus totalis - Case report and review of literature

      case-report

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          Abstract

          Introduction and importance

          Laparoscopic common bile duct (CBD) exploration with cholecystectomy in patients with situs inversus totalis (SIT) is technically demanding and warrants comprehensive knowledge of the mirror image anatomy along with laparoscopic orientation of the left upper quadrant.

          Case presentation

          In this case report, we present a female patient who presented with pain in the left hypochondrium, yellowish discoloration of the eyes since 2 months. She was evaluated, diagnosed to be a case of SIT with cholelithiasis and choledocholithiasis in cholangitis and endoscopic attempts for stone clearance failed. She subsequently underwent laparoscopic common bile duct exploration (LCBDE) with cholecystectomy. Per-operative, cystic duct was short and a choledochoscope was utilized for bile duct clearance.

          Clinical discussion

          Laparoscopic surgery in patients with SIT is complex, technically challenging and requires a in depth knowledge of remodeled anatomy. We noted a change in the relation of portal vein with CBD as in the portal vein was postero-lateral to bile duct rather than being completely posterior. The key here is to stay close to the common bile duct which can avoid confusion and inadvertent injury to vital structures in the hepato-duodenal ligament.

          Conclusion

          Laparoscopic cholecystectomy and CBD exploration in situs inversus is extremely challenging and the surgeon should be aware of the ergonomics and practice to operate laparoscopically with the opposite hand I.e the non-dominant hand in right-handed surgeon. Thus, laparoscopic cholecystectomy with LCBDE in situs inversus totalis is safe and feasible but demands technical difficulties.

          Highlights

          • Surgical management of biliary tract stones in patients with Situs inversus totalis (SIT) is technically complex.

          • A hepato-biliary surgeon should be aware of the altered anatomy since endoscopic management in these patient of SIT with choledocholithiasis often fails due to altered anatomy of duodenum.

          • This report highlights the challenges faced during laparoscopy in these patients and how to overcome them.

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          Most cited references10

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          The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines

          The Surgical CAse REport (SCARE) guidelines were first published in 2016 as a tool for surgeons to document and report their surgical cases in a standardised and comprehensive manner. However, with advances in technology and changes in the healthcare landscape, it is important to revise and update these guidelines to ensure they remain relevant and valuable for surgeons. Materials and methods: The updated guidelines were produced through a Delphi consensus exercise. Members of the SCARE 2020 guidelines Delphi group, editorial board members, and peer reviewers were invited to participate. Potential contributors were contacted by e-mail. An online survey was completed to indicate their agreement with the proposed changes to the guideline items. Results: A total of 54 participants were invited to participate and 44 (81.5%) completed the survey. There was a high degree of agreement among reviewers, with 36 items (83.7%) meeting the threshold for inclusion. Conclusion: Through a completed Delphi consensus exercise we present the SCARE 2023 guidelines. This will provide surgeons with a comprehensive and up-to-date tool for documenting and reporting their surgical cases while highlighting the importance of patient-centred care.
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            Situs Inversus Totalis: A Clinical Review

            Situs inversus totalis is a rare congenital abnormality characterized by a mirror-image transposition of both the abdominal and the thoracic organs. While this anomaly is known since the ancient times, practicing doctors do not have much experience with it. Laterality is established early in development, and any failure in that process might lead to a wide variety of disorders which may be partial or complete. Situs solitus describes the normal anatomy, situs inversus is the complete reversal, and situs ambiguous is used for any other abnormality of left-right development. Sidedness is regulated by genes: over 100 genes have been linked to laterality defects. Frequency of situs inversus is 1:10,000 and is more frequent in males: 1.5:1. Advanced imaging modalities can be used to assess fine anatomical details, which play a crucial role in these cases to plan radiologic or surgical interventions. Percutaneous biliary procedures, portal vein embolization are really challenging procedures in SIT patients due to the mirror effect. As most surgeons are right-handed, SIT operations can cause difficulties: handling the instruments with their left hand or the pedals with their left foot can be uncomfortable Organ, especially liver transplantation represents an extraordinary surgical challenge. Solutions to overcome the anatomic differences include the use of segment or reduced size graft with rotation, modified piggy-back technique, side to-side caval anastomosis, and vascular conduit. Because of its rarity and special nature, surgical patients with situs inversus may require more flexibility and creativity from the surgical team.
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              Laparoscopic cholecystectomy in situs inversus totalis: Feasibility and review of literature.

              Situs inversus totalis is a rare anomaly characterized by transposition of organs to the opposite site of the body. Laparoscopic cholecystectomy in those patients is technically more demanding and needs reorientation of visual-motor skills to left upper quadrant.

                Author and article information

                Contributors
                Journal
                Int J Surg Case Rep
                Int J Surg Case Rep
                International Journal of Surgery Case Reports
                Elsevier
                2210-2612
                29 March 2025
                May 2025
                29 March 2025
                : 130
                : 111238
                Affiliations
                Department of Surgical Gastroenterology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India
                Author notes
                [* ]Corresponding author at: Department of Surgical Gastroenterology, Jawaharlal Institute of Post Graduate Medical Education and Research (JIPMER), An Institution of National Importance, Government of India, Puducherry 605006, India. kalayarasanraja@ 123456yahoo.com
                Article
                S2210-2612(25)00424-9 111238
                10.1016/j.ijscr.2025.111238
                12005859
                40203625
                ff71ea5f-3b19-43ed-8217-9fc1ec68ade6
                © 2025 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Limited.

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                : 30 November 2024
                : 2 March 2025
                : 28 March 2025
                Categories
                Case Report

                laparoscopic common bile duct exploration,situs inversus totalis,choledocholithiasis,mirror image transposition,case report

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