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      Routes for breaching and protecting genetic privacy

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      Nature Reviews Genetics

      Springer Science and Business Media LLC

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          Abstract

          We are entering an era of ubiquitous genetic information for research, clinical care and personal curiosity. Sharing these data sets is vital for progress in biomedical research. However, a growing concern is the ability to protect the genetic privacy of the data originators. Here, we present an overview of genetic privacy breaching strategies. We outline the principles of each technique, indicate the underlying assumptions, and assess their technological complexity and maturation. We then review potential mitigation methods for privacy-preserving dissemination of sensitive data and highlight different cases that are relevant to genetic applications.

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          Most cited references 82

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          Communication Theory of Secrecy Systems*

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            k-ANONYMITY: A MODEL FOR PROTECTING PRIVACY

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              Calibrating Noise to Sensitivity in Private Data Analysis

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                Author and article information

                Journal
                Nature Reviews Genetics
                Nat Rev Genet
                Springer Science and Business Media LLC
                1471-0056
                1471-0064
                June 2014
                May 8 2014
                June 2014
                : 15
                : 6
                : 409-421
                Article
                10.1038/nrg3723
                4151119
                24805122
                © 2014

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