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      A Model of High-Dimensional Feature Reduction Based on Variable Precision Rough Set and Genetic Algorithm in Medical Image

      1 , 2 , 2 , 3 , 4 , 5
      Mathematical Problems in Engineering
      Hindawi Limited

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          Abstract

          Aiming at the shortcomings of high feature reduction using traditional rough sets, such as insensitivity with noise data and easy loss of potentially useful information, combining with genetic algorithm, in this paper, a VPRS-GA (Variable Precision Rough Set--Genetic Algorithm) model for high-dimensional feature reduction of medical image is proposed. Firstly, rigid inclusion of the lower approximation is extended to partial inclusion by classification error rate β in the traditional rough set model, and the ability dealing with noise data is improved. Secondly, some factors of feature reduction are considered, such as attribute dependency, attributes reduction length, and gene coding weight. A general framework of fitness function is put forward, and different fitness functions are constructed by using different factors such as weight and classification error rate β. Finally, 98 dimensional features of PET/CT lung tumor ROI are extracted to build decision information table of lung tumor patients. Three kinds of experiments in high-dimensional feature reduction are carried out, using support vector machine to verify the influence of recognition accuracy in different fitness function parameters and classification error rate. Experimental results show that classification accuracy is affected deeply by different weight values under the invariable classification error rate condition and by increasing classification error rate under the invariable weigh value condition. Hence, in order to achieve better recognition accuracy, different problems use suitable parameter combination.

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              Comparative evaluation of support vector machines for computer aided diagnosis of lung cancer in CT based on a multi-dimensional data set.

              Lung cancer is one of the most common forms of cancer resulting in over a million deaths per year worldwide. In this paper, the usage of support vector machine (SVM) classification for lung cancer is investigated, presenting a systematic quantitative evaluation against Boosting, Decision trees, k-nearest neighbor, LASSO regressions, neural networks and random forests. A large database of 5984 regions of interest (ROIs) and 488 input features (including textural features, patient characteristics, and morphological features) were used to train the classifiers and evaluate for their performance. The evaluation for classifiers' performance was based on a tenfold cross validation framework, receiver operating characteristic curve (ROC), and Matthews correlation coefficient. Area under curve (AUC) of SVM, Boosting, Decision trees, k-nearest neighbor, LASSO, neural networks, random forests were 0.94, 0.86, 0.73, 0.72, 0.91, 0.92, and 0.85, respectively. It was proved that SVM classification offered significantly increased classification performance compared to the reference methods. This scheme may be used as an auxiliary tool to differentiate between benign and malignant SPNs of CT images in future. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
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                Author and article information

                Journal
                Mathematical Problems in Engineering
                Mathematical Problems in Engineering
                Hindawi Limited
                1024-123X
                1563-5147
                May 30 2020
                May 30 2020
                : 2020
                : 1-18
                Affiliations
                [1 ]School of Computer Science and Engineering, North Minzu University, Yinchuan 750021, China
                [2 ]School of Science, Ningxia Medical University, Yinchuan 750004, China
                [3 ]School of Electronic & Information Engineering, Suzhou University of Science and Technology, Suzhou 215009, China
                [4 ]Key Laboratory of Spectral Imaging Technology CAS, Xi’an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi’an 710119, China
                [5 ]Human Resources Department, The Second Affiliated Hospital of Xiamen Medical College, Xiamen 361021, China
                Article
                10.1155/2020/7653946
                ffeb374e-1ad9-4629-a347-64dd7b39ec77
                © 2020

                http://creativecommons.org/licenses/by/4.0/

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