Science policy, as the theme appears in Prometheus over the last 20 years, has been represented by discussions of industrial competitiveness. Many comparative articles have appeared under this theme, as well as evaluations of policies aimed at innovation. By the mid‐1980s, articles in Prometheus were tracing the emergence of the knowledge economy, with some of its associated issues. The issue of human resources for the knowledge economy has received scant attention, however, but Prometheus authors have discussed public participation in science policymaking and setting priorities. Finally, authors have noted and analyzed the closer management of Australian science to direct it toward economic ends. Overall, Prometheus has tracked the dominant themes of science policy in other OECD countries well, and also given space to issues that are less prominent but nonetheless important.