Art, science, mathematics, technology, engineering and medicine became concentrated in silos around the time of the reformation. This both accelerated the disciplines whilst holding back the benefits to be gained from their linking. Today they are coming back together as a much-required force for innovation and understanding at a time when we are being progressively overtaken by vast amounts of data. This in turn demands complex combinations of modelling and visualisation to engender understanding, establish confidence and aid decision-making.