Pancreatic cancer currently has no cure in its advanced stage and often, systemic chemotherapy is used to improve survival and quality of life of patients. Chemotherapy treatments are available with varying degrees of benefits, harms, and uncertainties, and patients need to be aware of these characteristics and make informed choices or decide whether to avoid chemotherapy altogether. Web-based tools may help patients in making this informed choice with the help of their clinicians and relatives. Therefore, the aim of the study is to investigate the potential of a web-based interactive tool to support shared decision-making in the choice of treatment for people with advanced pancreatic cancer. A four-phase mixed methods paradigm has been adopted for the study. Participants will be clinicians (oncologists, clinical nurse specialists), people diagnosed with advanced (inoperable) pancreatic cancer, and relatives who support these patients. The first phase of the study identified 60 relevant citations on advanced pancreatic cancer treatment from four electronic databases from 1997 to 2018.