In this work the objective is to detect brain connectivity changes during epileptic seizures using methods of multivariate time series analysis on scalp multi-channel EEG. Different brain regions represented by the electrode positions interact in terms of Granger causality and these directed connections formulate the brain network at a certain time window. The numerous proposed network features are believed to capture the information of many network characteristics. The ability of a single network feature of the brain network to detect the transition of brain activity from preictal to ictal is examined. The connectivity of the brain is estimated by 13 Granger causality indices on 7 epochs from multivariate time series (19 channels per epoch) at 15 time windows of 20 seconds (5 min in total) before seizure and during the seizure. The characteristics of the networks are estimated by 379 network features. Finally, the discrimination task (preictal vs. ictal) for each network feature is evaluated by the area under receiver operating characteristic curve (AUROC).