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      Role of vitamins and nutrients in the management of attention-deficit hyperactivity disorder (ADHD): a narrative review

      Preprint
      In review
      research-article

            Revision notes

            As replied to the Reviewers individually

            Abstract

            Attention-deficit hyperactivity disorder (ADHD) is a common psychiatric disorder that affects individuals across all age groups, including children, adolescents, and adults. The etiology of ADHD involves lack of a number of nutrients and food components. However, certain dietary strategies have been suggested as additional therapy in this condition. Google Scholar, SCOPUS, and PubMed were among the databases searched for the studies. This review shed light on the correlation of dietary patterns with ADHD and to provide a concise summary of the current research about the practical application of dietary therapies. In the research, unhealthy eating habits were positively correlated with ADHD, but healthy eating habits were negatively correlated. Furthermore, there is a notable correlation between ADHD and a lack of certain nutrients, including iron, zinc, magnesium, polyunsaturated fatty acids (PUFAs) and vitamin D. The main limitation of this narrative review is the lack of scientific evidence. Although these dietary modifications are promising strategies for ADHD management, a stronger scientific proof is needed to be validated.

            Content

            Author and article information

            Journal
            ScienceOpen Preprints
            ScienceOpen
            4 May 2024
            Affiliations
            [1 ] Department of Pharmacology & Toxicology, Faculty of Pharmacy, Sinai University, El-Arish campus, North Sinai 45511, Egypt; rehab.mahmoud@su.edu.eg;
            [2 ] Nutrition and Food Science Department, University of Tabuk, Tabuk 71491, Saudi Arabia.;
            [3 ] Department of Physiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.;
            [4 ] PharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia.;
            [5 ] Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia.;
            Author notes
            Author information
            https://orcid.org/0000-0003-4403-9313
            https://orcid.org/0000-0001-5113-0495
            https://orcid.org/0000-0002-8160-7976
            https://orcid.org/0000-0002-9688-7683
            Article
            10.14293/PR2199.000797.v2
            e3a05ecb-3403-4770-b40c-682d7ecfbe52

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

            History
            : 29 March 2024
            Funding
            Funded by: funder-id http://dx.doi.org/10.13039/501100019345, King Salman Center for Disability Research;
            Award ID: KSRG-2023-104
            Categories

            Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
            Medicine
            ADHD,Minerals,Nutrients,Polyunsaturated fatty acids,Vitamins

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