GLIOBLASTOMA MULTIFORME: THE UNIQUE AND FATAL BRAIN TUMOR

Abstract

Glioblastomas are the most aggressive and most founded type of common type of CNS cancer which are mainly classified into 2 major groups i.e. low grade gliomas (LGG) and high grade gliomas (HGG) and exhibits both intra and inter tumor heterogeny

LGG are showing low proliferation rate and further divided two sub types that are Grade I and Grade II which are commonly infiltrative and recur and they occur usually due to mutations in IDH-1 and IDH-2 genes.

Whereas, HGG are further divided two sub types Grade III and Grade IV showing nuclear atypia and most aggressive necrosis and high angiogenesis rate.

Journal

Title: ScienceOpen Posters

Publisher: ScienceOpen

Publication date (Electronic preprint): 19 December 2020

Affiliations

[1 ] Department of Microbiology, G.G.D.S.D, PANJAB UNIVERSITY, CHANDIGARH, INDIA

[2 ] Department of BSBE, IIT Bombay, India

Article

DOI: 10.14293/S2199-1006.1.SOR-.PP2WBQG.v1

License:

This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .