Edible vaccine is cost effective, easy in administration, easy in storage and safe vaccine delivery system. Edible vaccines are prepared by molecular pharming using the science of genetic engineering. Selected genes which are pathogenic can be isolated from the source and then introduced into the plants. That plant is now called transgenic plant and it is able to produce the encoded protein. That protein is pathogenic which is used to give the people as an edible vaccine. That protein is used for therapeutic purposes. It is less costly rather than another vaccine. Resistance to genetically modified food may affect the future of edible vaccine.