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      Analysis of Human Genes Associated with Ebola using Online Bioinformatics Tools

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      ScienceOpen Preprints
      Ebola, gene networks, gene ontology, links diseases


            Ebola is a deadlydisease caused by a virus in the family of Filoviridae. The virion is a single-stranded RNA of negative polarity and proteins enclosed in a lipid membrane. This ebolavirus species in African countries has caused several severe epidemics. Its infection causes a rapidly fatal hemorrhagic fever in humans for which no approved antivirals are available. Currently, the diagnostic tests for this deadly disease are Enzyme-Linked Immunoassay (ELISA) and Polymerase Chain Reaction (PCR) tests; viral cultivation and biopsy samples may also be used. So, there is no standard treatment for Ebola hemorrhagic fever and only supportive therapy, and experimental treatment is available. We used online bioinformatics tools to understand and look for new therapeutic targets.


            Author and article information

            ScienceOpen Preprints
            21 December 2022
            [1 ] Institute of life sciences and biomedicine, Far Eastern Federal University
            [2 ] Institute of biotechnology,bioengineering and food systems, Far Eastern Federal University
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            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

            : 21 December 2022

            All data generated or analysed during this study are included in this published article (and its supplementary information files).
            Ebola,gene networks,gene ontology,links diseases


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