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      Gold standard method in testing laboratories: Is it appropriate or a misconception?

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      research-article
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      ScienceOpen Preprints
      ScienceOpen
      gold standard, culture, analytical, colony forming units, diagnostics
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            Abstract

            Gold standard is a very common but most powerful terminology amongst diagnostic and analytical laboratory scientists. The genesis dates back to 19th century monetary system where the standard economic unit of account is based on a fixed quantity of gold and has nothing to do with science. Nevertheless, this term had taken an indispensable place in the testing arena ever since its appearance in reputed scientific journals. Application of this term in analytical science from both proponents and opponents perspective has been discussed in detail. Its applicability with regards to bacteriological culture and pulsed field gel electrophoresis for typing bacteria and clinical diagnosis as examples are presented. In conclusion, diagnostic and analytical test methods should not be described or presented in a misleading manner as it is likely to create an erroneous impression on the use of such terminology. We need to revisit gold standard terminology for its appropriation.

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            Author and article information

            Journal
            ScienceOpen Preprints
            ScienceOpen
            28 October 2019
            Affiliations
            [1 ] Quality and Conformity Council, Abu Dhabi, United Arab Emirates
            Article
            10.14293/S2199-1006.1.SOR-.PP8SIYT.v1
            ae8bebb8-fd61-4a0b-94eb-58793cfa7b45

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

            Funding
            None None

            Life sciences
            gold standard,culture,analytical,colony forming units,diagnostics

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