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      Medication-Induced Neurotoxicity: Adverse Reactions to Drug Therapy

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            Abstract

            The drug-based treatment methods which have revolutionized modern medicine are vital in effective medical practice. While the use of drug therapy has benefited multitudes since its inception, it is imperative to note the consequences of chronic substance administration. Synthetic medications such as antibiotics, cancer-treating agents, and psychoactive modifiers are all linked to drug-induced neurotoxicity in patients. This results in adverse reactions that significantly increase morbidity, and in some cases, mortality. In this literary research report, potential implications associated with the use of select drugs within each corresponding class will be discussed.Examples of these select medications and their clinical intervention mechanisms are reviewed, and a recently published case report will be introduced for analysis of clinical presentation respective to each category. Analysis of literary review demonstrates correlation and causation between neurotoxicity and chronic medication use. These findings warrant cautionary administration of drugs in clinical practice, and call for increased research in efforts to advance recognition of drug-induced neurotoxicity in patients.

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            Author and article information

            Journal
            ScienceOpen Preprints
            ScienceOpen
            6 May 2022
            Affiliations
            [1 ] Kennesaw State University Honors College
            Author notes
            Author information
            https://orcid.org/0000-0002-5405-6881
            Article
            10.14293/S2199-1006.1.SOR-.PPBYMVZ.v1
            85f74c16-5d18-4278-9621-da1647ed72b1

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

            History
            : 6 May 2022

            All data generated or analysed during this study are included in this published article (and its supplementary information files).
            Medicine,Social & Behavioral Sciences,Life sciences
            neurotoxicity,psychopharmacology,psychophysiology,drug therapy,substance-induced neurotoxicity,antibiotics,cancer therapy,psychoactive drugs,adverse drug effects,neuronal modification

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