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      Leading Therapy Consequences to Leukemia

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            Abstract

            Second cancer risk following radiotherapy and chemotherapy is an increasingly important topic in clinical oncology with an impact on treatment decision making and patient management. And leukemia has one of the highest incidences. Much of the evidence that underlies our understanding of second cancer risks and our risk estimates are derived from large epidemiologic studies that we will talk about it and predictive models of earlier decades with large uncertainties. We will focus in our review on the mechanisms that lead to Therapy Related Leukemia and introduce the best strategies of cancer therapies to reduce the risk of second cancer such as Metronomic chemotherapy, hopefully, be used in cancer hospitals, our focus on this highly important issue had started after detection of a case for a cancer patient who was diagnosed with leukemia after a highly intensive regimen for breast cancer treatment which included high doses of chemotherapy and radiotherapy, therefore we aim to highlight the most updated safe administration of cancer treatments in this review to reduce such cases by oncologists worldwide.

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            Author and article information

            Journal
            ScienceOpen Preprints
            ScienceOpen
            11 May 2022
            Affiliations
            [1 ] Pharmacy College/Arab International University, Daraa, Ghabagheb, Syria
            Author notes
            Article
            10.14293/S2199-1006.1.SOR-.PPCW3FR.v1
            19d56950-e18f-4642-908b-457d9933053d

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .


            The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.
            Medicine
            Leukemia, Chemotherapy, Radiotherapy, Stem Cell Transplantation, Second Cancer, Metronomic Chemotherapy

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