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      Seroprevalence and factors associated with Syphilis infection among pregnant women living with HIV/AIDS in Mtwara region, Tanzania

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      ScienceOpen Posters
      ScienceOpen
      Syphilis, Seroprevalence
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            Abstract

            Background: Several studies in developing countries have shown that syphilis in pregnancy is a public health problem leading to perinatal morbidity and mortality. However, data on syphilis is limited in Tanzania and especially among pregnant women living with HIV.

            Methodology: A health facility-based cross-sectional study was conducted among pregnant women living with HIV/AIDS (LWHIV) in selected health facilities in Mtwara region. A structured questionnaire was used to collect clinical information from the study participants. A 4 mls of blood was collected for Syphilis screening and confirmatory tests using rapid tests and automated ELISA tests respectively.

            Results: Two hundred and twenty (n=220) pregnant women living with HIV/AIDS were enrolled in this study, with a median age of 32.7 years (IQR: 27.6-37.6). The majority (45.5%) of the participants were married, 71.4% had primary education, 47.7% were unemployed, 77.7% were multigravida and 40.5% were in second trimester. The seroprevalence of Syphilis infection and Syphilis-hepatitis B co-infection was 10.9% and 5.9 respectively. In this study, being in the second trimester of gestation period [aOR=5.69: 95% CI 1.44-22.46, p=0.013] and being infected with hepatitis B [aOR=31.39: 95% CI 9.45-104.23, p<0.001] were independently associated with HBV infection among PWLWHIV in Mtwara region.

            Conclusion: Seroprevalence of Syphilis infection and Syphilis-hepatitis B co-infection is 10.9% and 5.9 respectively. Additionally, being in the second trimester and being infected with HBV are factors associated with Syphilis infection among PWLHIV in Mtwara region. Therefore, scaling up Syphilis screening is crucial to prevent vertical transmission.

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            ScienceOpen Posters
            ScienceOpen
            1 October 2022
            Affiliations
            [1 ] Department of Epidemiology and Biostatistics, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
            [2 ] Department of Epidemiology and Biostatistics, Tanzania Field Epidemiology and Laboratory Training program, Dar es Salaam, Tanzania
            [3 ] Department of Microbiology and Immnunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
            Author notes
            Author information
            https://orcid.org/0000-0002-1939-2492
            Article
            10.14293/S2199-1006.1.SOR-.PPCWIUT.v1
            aa6528e7-e453-4956-9a0d-79639a0e3e9f

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

            History
            : 1 October 2022

            All data generated or analysed during this study are included in this published article (and its supplementary information files).
            Medicine
            Syphilis,Seroprevalence

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