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      SARS-COV-2 acts as a test of Air Pollution, Lifestyle Disorders and Immune Tolerance dysregulation in human body : A detailed skeletal mechanism of SARS-COV-2 and the underlying factors that help in it's manifestation of immune system in COVID-19 patients: Literature review till date

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      SARS-COV-2, COVID-19, immune system
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            Abstract

            SARS-COV-2 is reported to be associated with severe immune dysregulation, delayed humoral responses and accelerated innate immune response mediated damages. As the pandemic is turning the world upside down, In order to address this disease we should first get an insight into the mechanism of action through which SARS-COV-2 is achieving the above said dysregulating or modulating effects on human immune system. T

            his article presents the basic or skeletal mechanism through which SARS-COV-2 dysregulates immune system by targeting innate immune system, adaptive immune system and different immune tolerance check points by dysregulating different miRNA’s and the preexisting conditions or comorbidities of the patients. This article comprises of the comparative and comprehensive literature review targeting all topics with the data available/reported till date in the scientific community.

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            Author and article information

            Journal
            ScienceOpen Preprints
            ScienceOpen
            21 December 2021
            Affiliations
            [1 ] India
            Author notes
            Article
            10.14293/S2199-1006.1.SOR-.PPD7TYA.v1
            473f9e37-6620-43e9-8601-75c64f0279b2

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

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            Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
            Education,Medicine,Immunology,Human biology,Health & Social care,Public health,Infectious disease & Microbiology,Microbiology & Virology,Life sciences
            SARS-COV-2,immune system,COVID-19

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