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      The origin and language-like evolutionary behavior of proteins and translation : (untangled with deep-time chronologies and networks)

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            Abstract

            While the origin and early evolution of proteins and their biosynthetic mechanisms remain mysterious, advances in evolutionary genomics and systems biology are facilitating the historical exploration of the structure, function and organization of proteins and proteomes. Here we describe how chronologies and networks provide a window into the past and untangle the emergence of proteins, the development of the biosynthetic apparatus, and a language behind translation and ribosomal growth.

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            Author and article information

            Journal
            ScienceOpen Posters
            ScienceOpen
            29 May 2022
            Affiliations
            [1 ] University of Illinois at Urbana-Champaign;
            [2 ] Broad Institute of MIT and Harvard;
            Author notes
            Author information
            https://orcid.org/0000-0001-5854-4121
            https://orcid.org/0000-0001-5602-4042
            https://orcid.org/0000-0001-7704-0578
            Article
            10.14293/S2199-1006.1.SOR-.PPG9JLW.v1
            ec4d486c-d398-42aa-b753-c9ebdce991a7

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

            History
            : 29 May 2022
            Categories

            The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.
            Bioinformatics & Computational biology,Life sciences
            Loop,Phylogenomics,Domain,Ribosome,Proteome,Folding,Evolution

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