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      RNA Vaccine: The Future of Medical Science and Vaccinology

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      RNA Vaccine, Vaccinology , Next Generation Vaccine, Personalized Medicine

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          Abstract

          An attractive approach to vaccination is presented by nucleic acid vaccines. These vaccines based on DNA or RNA encoded with specific antigen and generally regarded as safe, effective which can mimic live infection with low rise of reversion to virulence. RNA vaccines generally elicit humoral as well as cellular immune response. Personalized medicine is the new paradigm of medical science for targeting specific characteristics of each individual by using their genetic profile to identify particular nature of the medical condition and design a unique treatment for each patient. Cancer immunotherapy stimulates a host antitumor immune response which can able to lead tumor shrinkage for the improvement of clinical outcomes in cancer patients. Eradication of the large tumor by active immunotherapy is the biggest challenge, to overcome this challenge combination therapy of mRNA vaccine with radiation can be effective. mRNA as a vaccine have many advantages including large scale production under GMP conditions is comparatively easy and robust, thats why inexpensive in contrast to the other biopharmaceuticals. The tumor antigens are recognizing by the immune system and this is the basis for cancer immunotherapy development.

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          Author and article information

          Journal
          ScienceOpen Posters
          ScienceOpen
          10 September 2020
          Affiliations
          [1 ] Department of Molecular Biology and Genetic Engineering, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara-144411, Punjab, India.
          Article
          10.14293/S2199-1006.1.SOR-.PPJBJXA.v1

          This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

          Data sharing not applicable to this article as no datasets were generated or analysed during the current study.

          Medicine, Life sciences

          RNA Vaccine, Personalized Medicine, Next Generation Vaccine, Vaccinology

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