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      Antisense Technology

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      Antisense Technology, RNAi Therapeutics, RNA Biology

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          Abstract

          Diseases are often connected on the expression of some disease causing gene which is important to produce that Protein. If the expression of this gene can be disputed then the disease can be cured. Antisense technology is a method of disputing the production of protein. It may be used to design some therapeutics for diseases in whose pathology is the production of protein plays a major role. Antisense technology is important tool in the inhibition of that particular gene expression. The principle behind it, is that the antisense nucleic acid sequence base pairs with its complementary sense RNA strand is inserted and prevents the RNA from translated into protein. The complementary nucleic acid sequence is either complementary synthetic oligonucleotide, often oligodeoxy ribonucleotide, or longer antisense RNA sequence.

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          Author and article information

          Journal
          ScienceOpen Posters
          ScienceOpen
          15 November 2019
          Affiliations
          [1 ] Department of Biotechnology, Veer Narmad South Gujarat University, Surat 395007, Gujarat, India.
          Article
          10.14293/S2199-1006.1.SOR-.PPQGNNU.v1

          This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

          Medicine, Life sciences

          Antisense Technology, RNAi Therapeutics, RNA Biology

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