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      COVID-19 And SARS-COV-2 Infection And Virulence: Hypothesis I

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      ScienceOpen Preprints
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      COVID-19, SARS-COV-2, Infectivity, Virulence, DP10000 Number
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            Abstract

            SARS-COV-2 is the etiologic agent of COVID-19. There is currently no effective means of preventing infections by SARS-COV-2, except through restriction of population movement and contact. An understanding of the origin, evolution and biochemistry (molecular biology) of SARS-COV-2 is a prerequite to its control. There is no definitive answer as to the origin of SARS-COV-2. The evolution of SARS-COV-2 can be gleaned from a comparative study of its infectivity and virulence in different populations and environments. From an analysis of the infectivity and virulence of SARS-COV-2 in different parts of the world, it is submitted that there is no correlation between infectivity and virulence of SARS-COV-2. It is therefore hypothesized that SARS-COV-2 may be a rapidly mutating virus and identification of SARS-COV-2 strain(s) that has/have increased virulence is essential in the formulation of any effective vaccine or prophylactic that targets SARS-COV-2.

            Content

            Author and article information

            Journal
            ScienceOpen Preprints
            ScienceOpen
            10 April 2020
            Affiliations
            [1 ] Nachbraht Biomedical Research Institute
            Article
            10.14293/S2199-1006.1.SOR-.PPXVKPX.v1
            6d2142de-a0a1-497e-9433-0ed3a59668c1

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .


            The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.
            Biochemistry,Molecular medicine,Molecular biology,Microbiology & Virology
            Virulence,SARS-COV-2,DP10000 Number,Infectivity,COVID-19

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