Wits Journal of Clinical Medicine Conversations presents Prof Pravin Manga (Editor of the Wits Journal of Clinical Medicine) and Prof Shabhir Madhi (Dean of Health Sciences at Wits University) discuss the new Covid-19 variant XBB.1.5 and its potential impact in South Africa. Recorded January 2023. Access the latest issue of the Wits Journal of Clinical Medicine in March 2023 (https://journals.co.za/journal/wjcm).