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The next variant of SARS-CoV-2: what’s next after Omicron VOC in India?
Abstract
"Omicron", a variant of concern ( VoC) brought a fresh 3rd epidemic wave of SARS-CoV-2 infections in India and concern at the start of January 2022 to the end of February. From March 2022, India and other countries started recording decline in RT-PCR and RT positive case numbers and also deaths from severe SARS Cov2 in West Bengal, a province in India as of 6.03.22 reported positive cases were only 90 and 2 deaths but the number started to raise in the third week of March 22. By 19/03/22, in India 2075 positive cases were reported with 71 deaths while in West Bengal province 347 positive cases and 1 death was reported. After two years of an oscillating pendulum between pandemic surges and temporary lockdowns since early 2020, people in India and in other countries including doctor scientists are wondering of the when and how the next wave of SARS cov2 if it will come in India — and in what form it will take in India (same like B1.1.529 subtype BA1 or it will be BA2 the stealth variant of concern like at Europe or in China or South Korea?) Many people think however it is inevitable that we will possibly observe new variants (BA2/ BA3) with varying degrees of immune evasion with the prediction that these variant can emerge from anywhere if there is widespread transmission now like in Europe, China Korea and in some countries of South Asia and will come to India by air flight from these countries. A lot of basic scientists are studying the currently dominant Omicron variant to predict the future; three basic questions scientists should attempt to answer: when will the next variant of concern emerge? Should it emerge whether there will be different variants of concern (VOC)? What will be the fatality rate when new variant emerges?
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