A booming economy, a weak judicial system, and institutionalized corruption are the perfect match of circumstances that attract transnational organized crime into Panamanian territory. These organizations make collaborations with local gangs to transport drugs, increasing the associated number of violent crimes. This case study will express an understanding of the issues in Panama’s Public Security system, using Systems Thinking and DSRP (Distinction, Systems, Relationships, and Perspectives) rules, while presenting findings and recommendations for future public security policy and strategies after the application of the ABA (Agent-Based Approach) method.