Milestones in the discovery and clinical translation of regulatory T cells (Tregs), a subset of suppressive T lymphocytes that hold the potential to treat autoimmune disorders and organ transplant rejection.
References include seminal studies on murine Tregs, human Tregs, and redirecting T cell specificity via genetic modification, including engineered T cell receptor (TCR) and chimeric antigen receptor (CAR) based approaches.
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|ScienceOpen disciplines:||Medicine, Transplantation, Immunology|
|Keywords:||Regulatory T cell, Treg, Cell therapy, Autoimmunity, Transplant|