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      Stem cells and cancer: two faces of eve.

      Cell
      Cell Differentiation, Cell Proliferation, Humans, Neoplasm Metastasis, pathology, Neoplasms, etiology, prevention & control, Stem Cells

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          Abstract

          Recent evidence suggests that a subset of cancer cells within some tumors, the so-called cancer stem cells, may drive the growth and metastasis of these tumors. Understanding the pathways that regulate proliferation, self-renewal, survival, and differentiation of malignant and normal stem cells may shed light on mechanisms that lead to cancer and suggest better modes of treatment.

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          Journal
          16564000
          10.1016/j.cell.2006.03.011

          Chemistry
          Cell Differentiation,Cell Proliferation,Humans,Neoplasm Metastasis,pathology,Neoplasms,etiology,prevention & control,Stem Cells

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