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      Prediction of the number of deaths in India due to SARS-CoV-2 at 5–6 weeks

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          Abstract

          Introduction

          and Aims: No valid treatment or preventative strategy has evolved till date to counter the SARS CoV 2 (Novel Coronavirus) epidemic that originated in China in late 2019 and have since wrought havoc on millions across the world with illness, socioeconomic recession and death. This analysis was aimed at tracing a trend related to death counts expected at the 5th and 6th week of the COVID-19 in India.

          Material and methods

          Validated database was used to procure global and Indian data related to coronavirus and related outcomes. Multiple regression and linear regression analyses were used interchangeably. Since the week 6 death count data was not correlated significantly with any of the chosen inputs, an auto-regression technique was employed to improve the predictive ability of the regression model.

          Results

          A linear regression analysis predicted average week 5 death count to be 211 with a 95% CI: 1.31–2.60). Similarly, week 6 death count, in spite of a strong correlation with input variables, did not pass the test of statistical significance. Using auto-regression technique and using week 5 death count as input the linear regression model predicted week 6 death count in India to be 467, while keeping at the back of our mind the risk of over-estimation by most of the risk-based models.

          Conclusion

          According to our analysis, if situation continue in present state; projected death rate (n) is 211 and467 at the end of the 5th and 6th week from now, respectively.

          Highlights

          • This analysis was aimed at tracing a trend related to death counts expected at the 5th and 6th week of the COVID-19 in India.

          • According to our analysis, if situation continue in present state; projected death rate (n) is 211 and 467 at the end of the 5th and 6th week from now, respectively.

          • Keeping these projected mortality data in mind, current measured for containment of COVID-19 must be strengthened or supplemented.

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          Most cited references2

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          COVID-19 and the consequences of isolating the elderly

          As countries are affected by coronavirus disease 2019 (COVID-19), the elderly population will soon be told to self-isolate for “a very long time” in the UK, and elsewhere. 1 This attempt to shield the over-70s, and thereby protect over-burdened health systems, comes as worldwide countries enforce lockdowns, curfews, and social isolation to mitigate the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, it is well known that social isolation among older adults is a “serious public health concern” because of their heightened risk of cardiovascular, autoimmune, neurocognitive, and mental health problems. 2 Santini and colleagues 3 recently demonstrated that social disconnection puts older adults at greater risk of depression and anxiety. If health ministers instruct elderly people to remain home, have groceries and vital medications delivered, and avoid social contact with family and friends, urgent action is needed to mitigate the mental and physical health consequences. Self-isolation will disproportionately affect elderly individuals whose only social contact is out of the home, such as at daycare venues, community centres, and places of worship. Those who do not have close family or friends, and rely on the support of voluntary services or social care, could be placed at additional risk, along with those who are already lonely, isolated, or secluded. Online technologies could be harnessed to provide social support networks and a sense of belonging, 4 although there might be disparities in access to or literacy in digital resources. Interventions could simply involve more frequent telephone contact with significant others, close family and friends, voluntary organisations, or health-care professionals, or community outreach projects providing peer support throughout the enforced isolation. Beyond this, cognitive behavioural therapies could be delivered online to decrease loneliness and improve mental wellbeing. 5 Isolating the elderly might reduce transmission, which is most important to delay the peak in cases, and minimise the spread to high-risk groups. However, adherence to isolation strategies is likely to decrease over time. Such mitigation measures must be effectively timed to prevent transmission, but avoid increasing the morbidity of COVID-19 associated with affective disorders. This effect will be felt greatest in more disadvantaged and marginalised populations, which should be urgently targeted for the implementation of preventive strategies.
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            • Record: found
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            The species Severe acute respiratory syndromerelated coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Coronaviridae Study Group of the International Committee on Taxonomy of Viruses

            (2020)
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              Author and article information

              Contributors
              Journal
              Diabetes Metab Syndr
              Diabetes Metab Syndr
              Diabetes & Metabolic Syndrome
              Diabetes India. Published by Elsevier Ltd.
              1871-4021
              1878-0334
              2 April 2020
              2 April 2020
              :
              Affiliations
              [a ]Consultant Endocrinologist. Nightingale Hospital, Kolkata, India
              [b ]Consultant Pulmonologist. AMRI Hospitals, Kolkata, India
              [c ]Milan Majumder, Independent Statistician, Pune, India
              [d ]Consultant Endocrinologist. AMRI Hospitals, Kolkata, India
              Author notes
              []Corresponding author. ramdasghosal@ 123456gmail.com
              Article
              S1871-4021(20)30057-6
              10.1016/j.dsx.2020.03.017
              7128942
              63aba9ce-9f5e-4536-a7ec-ab4de5d74024
              © 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved.

              Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

              History
              : 26 March 2020
              : 27 March 2020
              : 27 March 2020
              Categories
              Article

              india,coronavirus,death rates,correlation,regression
              india, coronavirus, death rates, correlation, regression

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