Since the description of its eight species, the Mesoamerican genus Phrynidius Lacordaire (Cerambycidae, Lamiinae, Apomecynini) has not been comprehensively studied, with only a few distributional records published in recent years. In this work, four new species of Phrynidius are described from Chiapas, Mexico: P. cristinae sp. nov. from the municipality of Escuintla, P. diminutus sp. nov. from San Cristobal, Phrynidius jonesi sp. nov. from Trinitaria, and P. tuberculatus sp. nov. from Jaltenango. An updated taxonomic key and illustrations of the new species are also provided.