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      A comparative pharmacological investigation of Ashwagandha and Ginseng.

      Journal of Ethnopharmacology
      Administration, Oral, Animals, Body Weight, drug effects, Chromatography, Thin Layer, Male, Mice, Muscles, Panax, Physical Exertion, Plant Extracts, Plants, Medicinal, Rats, Stress, Physiological, prevention & control, Swimming, Withania

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          Abstract

          The aqueous suspensions of roots of an Indian drug Ashwagandha and the Korean drug Ginseng were tested comparatively for 2 pharmacological activities, namely the anti-stress activity by the 'mice swimming endurance test' and anabolic activity by noting gain in body weights and levator ani muscle in rats. A significant increase in mice swimming time was shown by Ginseng (P < 0.001) and Ashwagandha (P < 0.01) as compared to the control group. Significant increase in body weights in the Ashwagandha treated group (P < 0.05) was better than Ginseng (P < 0.5). Gain in wet weights of the levator ani muscle were also significant in Ginseng (P < 0.001) and Ashwagandha (P < 0.01) treated groups, however, the weight gain of dried levator ani muscles showed comparable results for both these drugs (P < 0.01).

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