Responses of dural mast cells in concussive and blast models of mild traumatic brain injury in mice: Potential implications for post-traumatic headache.

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Abstract

Chronic post-traumatic headache (PTH) is one of the most common symptoms of mild traumatic brain injury (mTBI) but its underlying mechanisms remain unknown. Inflammatory degranulation of dural mast cells (MCs) is thought to promote headache, and may play a role in PTH. Whether mTBI is associated with persistent degranulation of dural MCs is yet to be determined.

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Journal

Journal ID (iso-abbrev): Cephalalgia

Title: Cephalalgia : an international journal of headache

Publisher: SAGE Publications

ISSN (Electronic): 1468-2982

ISSN (Print): 0333-1024

Publication date (Electronic): Sep 2016

Volume: 36

Issue: 10

Affiliations

[1 ] Department of Anesthesia Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, USA Harvard Medical School, USA dlevy1@bidmc.harvard.edu.

[2 ] Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Israel.

[3 ] Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Israel Sagol School of Neuroscience, Tel Aviv University, Israel.

[4 ] Department of Anesthesia Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, USA Harvard Medical School, USA.

[5 ] Department of Anesthesia Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, USA.

[6 ] Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Israel Sagol School of Neuroscience, Tel Aviv University, Israel.

Article

Publisher Item ID: 0333102415617412

DOI: 10.1177/0333102415617412

PubMed ID: 26566937

SO-VID: a9e37055-fa05-4062-9f9d-4f522a34e307

History

Keywords: Minimal traumatic brain injury,blast,concussion,dura,mast cell,mouse,posttraumatic headache

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Keywords: Minimal traumatic brain injury, blast, concussion, dura, mast cell, mouse, posttraumatic headache

Responses of dural mast cells in concussive and blast models of mild traumatic brain injury in mice: Potential implications for post-traumatic headache.

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