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      A randomized controlled clinical trial of Ocimum sanctum and chlorhexidine mouthwash on dental plaque and gingival inflammation.

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          Abstract

          Periodontal diseases are ubiquitous, affecting all dentate animals. Regular methods for controlling it have been found to be ineffective, which have paved the way for the use of herbal products as an adjunctive to mechanical therapy as they are free to untoward effects and hence can be used for a long period of time. Ocimum sanctum is a plant which has the greater medicinal value and enormous properties for curing and preventing disease.

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          Most cited references27

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          EXPERIMENTAL GINGIVITIS IN MAN.

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            Reduced plaque formation by the chloromethyl analogue of victamine C.

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              Ocimum sanctum Linn. A reservoir plant for therapeutic applications: An overview

              The medicinal plants are widely used by the traditional medicinal practitioners for curing various diseases in their day to day practice. In traditional system of medicine, different parts (leaves, stem, flower, root, seeds and even whole plant) of Ocimum sanctum Linn. have been recommended for the treatment of bronchitis, malaria, diarrhea, dysentery, skin disease, arthritis, eye diseases, insect bites and so on. The O. sanctum L. has also been suggested to possess anti-fertility, anticancer, antidiabetic, antifungal, antimicrobial, cardioprotective, analgesic, antispasmodic and adaptogenic actions. Eugenol (1-hydroxy-2-methoxy-4-allylbenzene), the active constituents present in O. sanctum L. have been found to be largely responsible for the therapeutic potentials. The pharmacological studies reported in the present review confirm the therapeutic value of O. sanctum L. The results of the above studies support the use of this plant for human and animal disease therapy and reinforce the importance of the ethno-botanical approach as a potential source of bioactive substances.
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                Author and article information

                Journal
                J Ayurveda Integr Med
                Journal of Ayurveda and integrative medicine
                Medknow
                0975-9476
                0975-9476
                Apr 2014
                : 5
                : 2
                Affiliations
                [1 ] Department of Public Health Dentistry, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, India.
                [2 ] Government Post Graduate College, Lansdowne, Uttrakhand, India.
                [3 ] Department of Orthodontics and Dentofacial Orthopaedics, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, India.
                [4 ] Department of Anesthesiology, Maulana Azad Medical College, New Delhi, India.
                Article
                JAIM-5-109
                10.4103/0975-9476.131727
                4061585
                24948862
                eba7b0bf-69f8-4459-a1ec-f4efdd4db6f3
                History

                gingival index,Chlorhexidine,plaque index,Ocimum sanctum

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