Queratosis seborreica de la conjuntiva: informe de un caso

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Abstract

Caso clínico: Las lesiones conjuntivales pigmentadas representan un reto diagnóstico para el clínico. Hombre de 37 años de edad quien presentó una masa conjuntival pigmentada en su ojo derecho. Clínicamente se diagnosticó como melanoma, por lo que se realizó escisión completa del tumor. El diagnóstico histopatológico fue de queratosis seborreica. Discusión: La queratosis seborreica es una lesión benigna que se presenta en los párpados y en la cara de individuos de edad media y adultos mayores. El desarrollo de esta lesión en la conjuntiva es poco frecuente, solo se han informado 2 casos en la literatura. La queratosis seborreica debe ser considerada en el diagnóstico diferencial de lesiones conjuntivales pigmentadas.

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Most cited references 7

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Conjunctival Melanoma

Stefan Seregard (1998)

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Conjunctival melanoma.

S Seregard (2015)

Conjunctival melanoma is an uncommon tumor that is likely to recur and carries an overall mortality rate of approximately 30%. The seemingly unpredictable and enigmatic character of this entity has initiated much debate over the past decades regarding the etiology, histogenesis, prognosis, and preferred management. This review outlines the historical perspective; incidence and demographics; etiologic factors; histogenesis; cytogenetic findings; clinical characteristics; histopathologic and ultrastructural features; differential diagnoses; classifications; management of primary, recurrent, and systemic disease; survival after conjunctival melanoma; and diverse factors of potential prognostic significance. Finally, a brief outlook on present and future research objectives is provided.

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Seborrheic keratosis of conjunctiva simulating a malignant melanoma: an immunocytochemical study with impression cytology.

M-H Tseng, Q. Jin, Eric Chen … (1999)

Seborrheic keratosis on the conjunctiva appears to have never been reported in the literature. The authors report here a well-documented case of seborrheic keratosis of conjunctiva clinically simulating a malignant melanoma. Case report. A 66-year-old man presented with a juxtalimbal pigmented tumor involving the temporal conjunctiva of his left eye. Because of the rapid enlargement of the mass within a period of 5 months, a clinical diagnosis of malignant melanoma was made. Cytopathologic examinations were performed by impression cytology before the patient underwent a wide en-block excision of the tumor. Cytologic features were studied by impression cytology with periodic acid-Schiff-Papanicolaou stain. Immunochemical characteristics of tumor cells were studied by immunochemical stain of cytokeratin and HMB-45. Tumor morphology was observed by histopathologic examination. Impression cytology disclosed basaloid cells intermixing with squamoid cells, and these cells demonstrated positive immunoreactivity to cytokeratin and no reactivity to HMB-45. Histopathologic examination of the tumor specimen established the diagnosis of seborrheic keratosis, and the results of immunohistochemical staining were consistent with those of the impression cytology with immunocytochemical staining. The authors describe the first case report of conjunctival seborrheic keratosis and present its immunocytochemical and immunohistochemical characteristics. Such a benign lesion can clinically mimic a malignant melanoma.