Aging-related Repositioned Drugs, Donepezil and Sildenafil Citrate, Increase Apoptosis of Anti-mitotic Drug-resistant KBV20C Cells Through Different Molecular Mechanisms.

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Abstract

The study focused on identifying the mechanisms or drugs that could sensitize P-glycoprotein (P-gp)-overexpressing resistant KBV20C cancer cells to halaven (HAL) or vincristine (VIC) treatment.

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Journal

Journal ID (iso-abbrev): Anticancer Res

Title: Anticancer research

Publisher: Anticancer Research USA Inc.

ISSN (Electronic): 1791-7530

ISSN (Print): 0250-7005

Publication date (Electronic): Sep 2018

Volume: 38

Issue: 9

Affiliations

[1 ] School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.

[2 ] School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea syoon88@gmail.com.

Article

Publisher Item ID: 38/9/5149

DOI: 10.21873/anticanres.12837

PubMed ID: 30194162

SO-VID: 70ec8002-7ad2-4939-806f-254e5497cc81

History

Keywords: Donepezil,P-gp,apoptosis,cancer,drug resistance,repositioning drug,sildenafil citrate

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Keywords: Donepezil, P-gp, apoptosis, cancer, drug resistance, repositioning drug, sildenafil citrate

Aging-related Repositioned Drugs, Donepezil and Sildenafil Citrate, Increase Apoptosis of Anti-mitotic Drug-resistant KBV20C Cells Through Different Molecular Mechanisms.

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Drug Repurposing Research Collection

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