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      Aging-related Repositioned Drugs, Donepezil and Sildenafil Citrate, Increase Apoptosis of Anti-mitotic Drug-resistant KBV20C Cells Through Different Molecular Mechanisms.

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          Abstract

          The study focused on identifying the mechanisms or drugs that could sensitize P-glycoprotein (P-gp)-overexpressing resistant KBV20C cancer cells to halaven (HAL) or vincristine (VIC) treatment.

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          Author and article information

          Journal
          Anticancer Res
          Anticancer research
          Anticancer Research USA Inc.
          1791-7530
          0250-7005
          Sep 2018
          : 38
          : 9
          Affiliations
          [1 ] School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
          [2 ] School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea syoon88@gmail.com.
          Article
          38/9/5149
          10.21873/anticanres.12837
          30194162
          70ec8002-7ad2-4939-806f-254e5497cc81
          Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
          History

          Donepezil,P-gp,apoptosis,cancer,drug resistance,repositioning drug,sildenafil citrate

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