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      Drug Design, Development and Therapy (submit here)

      This international, peer-reviewed Open Access journal by Dove Medical Press focuses on the design and development of drugs, as well as the clinical outcomes, patient safety, and programs targeted at the effective and safe use of medicines. Sign up for email alerts here.

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      Profile of gantenerumab and its potential in the treatment of Alzheimer’s disease [Corrigendum]

      Drug Design, Development and Therapy
      Dove Medical Press

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          Abstract

          Novakovic D, Feligioni M, Scaccianoce S, et al. Drug Des Devel Ther. 2013;7:1359–1364. On page 1362, left hand column, last sentence under Functional studies: The effects of gantenerumab on cognitive assessment in the Morris water maze test were inconclusive, as both wild-type and transgenic AD mice injected with vehicle displayed impairment of learning, which might be ascribed to stress conditions caused by weekly intracerebroventricular injections. Importantly, neurological or motor impairments were not detected even after 5 months of treatment.24 Should read as: The effects of gantenerumab on cognitive assessment in the Morris water maze test were inconclusive, as both wild-type and transgenic AD mice injected with vehicle displayed impairment of learning, which might be ascribed to stress conditions caused by weekly intravenous injections. Importantly, neurological or motor impairments were not detected even after 5 months of treatment.24

          Author and article information

          Journal
          4035248
          10.2147/DDDT.S58818
          http://creativecommons.org/licenses/by-nc/3.0/

          Pharmacology & Pharmaceutical medicine
          Pharmacology & Pharmaceutical medicine

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