The relations of age and pubertal development with cortisol and daily stress in youth at clinical risk for psychosis.

Moskow, Danielle M; Addington, Jean; Bearden, Carrie E.; Cadenhead, Kristin S; Cornblatt, Barbara A.; Heinssen, Robert K; Mathalon, Daniel H.; McGlashan, Thomas H; Perkins, Diana O.; Seidman, Larry J.; Tsuang, Ming T.; Cannon, Tyrone D.; Woods, Scott W

doi:10.1016/j.schres.2016.02.002

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The relations of age and pubertal development with cortisol and daily stress in youth at clinical risk for psychosis.

Author(s): Danielle M Moskow ¹ , Jean Addington ² , Carrie E Bearden ³ , Kristin S Cadenhead ⁴ , Barbara A Cornblatt ⁵ , Robert Heinssen ⁶ , Daniel H Mathalon ⁷ , Thomas H McGlashan ⁸ , Diana O Perkins ⁹ , Larry J Seidman ¹⁰ , Ming T Tsuang ¹¹ , Tyrone D Cannon ¹² , Scott W Woods ¹³ , Elaine F Walker ¹⁴

Publication date (Electronic): Apr 2016

Journal: Schizophrenia research

Publisher: Elsevier BV

Keywords: Clinical high risk, Cortisol, Psychosis, Puberty, Schizophrenia, Stress

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Abstract

Prodromal syndromes often begin in adolescence - a period of neurodevelopmental changes and heightened stress sensitivity. Research has shown elevated stress and cortisol in individuals at clinical high risk (CHR) for psychosis. This cross-sectional study examined relations of age and pubertal status with cortisol and self-reported stress in healthy controls (HCs) and CHR adolescents. It was hypothesized that the relations of age and pubertal stage with cortisol and stress would be more pronounced in CHR youth.

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Journal ID (iso-abbrev): Schizophr. Res.

Title: Schizophrenia research

Publisher: Elsevier BV

ISSN (Electronic): 1573-2509

ISSN (Print): 0920-9964

Publication date (Electronic): Apr 2016

Volume: 172

Issue: 1-3

Affiliations

[1 ] Emory University, 36 Eagle Row, Atlanta, GA 30322, USA. Electronic address: dmoskow@nyspi.columbia.edu.

[2 ] University of Calgary, 3280 Hospital Drive NW, Calgary, AB T2N 4Z6, Canada. Electronic address: jmadding@ucalgary.ca.

[3 ] Univeristy of California, 300 Medical Plaza Suite 2265, Los Angeles, CA 90095, USA. Electronic address: cbearden@mednet.ucla.edu.

[4 ] University of California, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address: kcadenhead@ucsd.edu.

[5 ] Zucker Hillside Hospital, Glen Oaks, NY 11004, USA. Electronic address: cornblat@lij.edu.

[6 ] National Institute of Mental Health, 6001 Executive Boulevard, Bethesda, MD 20893, USA. Electronic address: rheinsse@mail.nih.gov.

[7 ] University of California San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA. Electronic address: Daniel.Mathalon@ucsf.edu.

[8 ] Yale University, 300 George Street, New Haven, CT 06511, USA. Electronic address: thomas.mcglashan@yale.edu.

[9 ] University of North Carolina, 101 Manning Dr, Chapel Hill, NC 27514, USA. Electronic address: diana_perkins@med.unc.edu.

[10 ] Harvard University, 55 Friot Street, Boston, MA 02114, USA. Electronic address: lseidman@caregroup.harvard.edu.

[11 ] University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA. Electronic address: mtsuang@ucsd.edu.

[12 ] Yale University, 1 Prospect Street, New Haven, CT 06511, USA. Electronic address: tyrone.cannon@yale.edu.

[13 ] Yale University, 300 George Street, New Haven, CT 06511, USA. Electronic address: scott.woods@yale.edu.

[14 ] Emory University, 36 Eagle Row, Atlanta, GA 30322, USA. Electronic address: psyefw@emory.edu.

Article

Publisher Item ID: S0920-9964(16)30058-5 Mid ID: NIHMS762149

DOI: 10.1016/j.schres.2016.02.002

PMC ID: 4821739

PubMed ID: 26905038

SO-VID: 133bc3be-33ac-4805-ba1c-58bcad79c6e2

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Keywords: Clinical high risk,Cortisol,Psychosis,Puberty,Schizophrenia,Stress

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Keywords: Clinical high risk, Cortisol, Psychosis, Puberty, Schizophrenia, Stress

The relations of age and pubertal development with cortisol and daily stress in youth at clinical risk for psychosis.

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