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      Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy

      Author(s): , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,
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      Journal: New England Journal of Medicine
      Publisher: Massachusetts Medical Society

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          Abstract

          <p class="first" id="d5276e440">New England Journal of Medicine, 373(10), 929-938</p>

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          Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy.

          Scott W Sharkey, Denise Windenburg, John Lesser … (2010)
          This study was designed to define more completely the clinical spectrum and consequences of stress cardiomyopathy (SC) beyond the acute event. Stress cardiomyopathy is a recently recognized condition characterized by transient cardiac dysfunction with ventricular ballooning. Clinical profile and outcome were prospectively assessed in 136 consecutive SC patients. Patients were predominantly women (n = 130; 96%), but 6 were men (4%). Ages were 32 to 94 years (mean age 68 +/- 13 years); 13 (10%) were 2 months in 5%. Right and/or left ventricular thrombi were identified in 5 patients (predominantly by CMR imaging), including 2 with embolic events. Three patients (2%) died in-hospital and 116 (85%) have survived, including 5% with nonfatal recurrent SC events. All-cause mortality during follow-up exceeded a matched general population (p = 0.016) with most deaths occurring in the first year. In this large SC cohort, the clinical spectrum was heterogeneous with about one-third either male,
          Article 0 comments Cited 223 times – based on 0 reviews     Review now
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            The brain-heart connection.

            Benjamin A. Samuels (2007)
            Article 0 comments Cited 156 times – based on 0 reviews     Review now
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              Four-year recurrence rate and prognosis of the apical ballooning syndrome.

              Ahmad Elesber, Abhiram Prasad, Ryan Lennon … (2007)
              This study sought to assess the long-term prognosis of patients with apical ballooning syndrome (ABS). Apical ballooning syndrome is a recently described acute cardiac syndrome of uncertain etiology and prognosis. We retrospectively identified 100 unselected patients with a confirmed diagnosis of ABS by angiography. Recurrences of ABS and mortality were recorded. Over a mean follow-up of 4.4 +/- 4.6 years, 31 patients continued to have episodes of chest pain and 10 patients had recurrence of ABS, for a recurrence rate of 11.4% over the first 4 years. Seventeen patients died in 4.7 +/- 4.8 years of follow-up. There was no difference in survival or in cardiovascular survival to an age- and gender-matched population. The recurrence rate for ABS was 11.4% over 4 years after initial presentation. Recurrence of chest pain is common. Four-year survival was not different from that in an age-matched and gender-matched population.
              Article 0 comments Cited 115 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Title: New England Journal of Medicine
                Abbreviated Title: N Engl J Med
                Publisher: Massachusetts Medical Society
                ISSN (Print): 0028-4793
                ISSN (Electronic): 1533-4406
                Publication date Created: September 03 2015
                Publication date (Print): September 03 2015
                Volume: 373
                Issue: 10
                Pages: 929-938
                Article
                DOI: 10.1056/NEJMoa1406761
                SO-VID: eb7ecb77-f881-4b96-818e-3ba80df1b605
                Copyright © © 2015
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