Structure Regulates Phage Lysis-Lysogeny Decisions.

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Abstract

There are many strategies by which cell fates are decided. In one intriguing case, viruses communicate via the quorum-sensing-like 'arbitrium' system to bias infection outcomes. Through elucidating the detailed molecular mechanisms of such strategies, we can better understand viral propagation and offer insights into the treatment of viral diseases.

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Author and article information

Journal

Journal ID (iso-abbrev): Trends Microbiol

Title: Trends in microbiology

Publisher: Elsevier BV

ISSN (Electronic): 1878-4380

ISSN (Print): 0966-842X

Publication date (Electronic): Jan 2019

Volume: 27

Issue: 1

Affiliations

[1 ] Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA; Center for Phage Technology, Texas A&M University, College Station, TX 77843, USA.

[2 ] Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA; Center for Phage Technology, Texas A&M University, College Station, TX 77843, USA. Electronic address: lzeng@tamu.edu.

Article

Publisher Item ID: S0966-842X(18)30255-5

DOI: 10.1016/j.tim.2018.11.005

PubMed ID: 30502931

SO-VID: 2af7ce19-604e-4c4b-bb6f-7754b322b2e3

History

Keywords: cell fate decision,bacteriophage,lysis–lysogeny

Data availability:

Keywords: cell fate decision, bacteriophage, lysis–lysogeny

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