Much effort has been applied in estimating the concentrations of chlorophyll-a (Chl a) in lakes. The optical complexity and lack of in situ data complicate estimating Chl a in such water bodies. We compared four established satellite reflectance algorithms—the two-band and three-band algorithms (2BDA, 3BDA), fluorescence line height (FLH), and normalized difference chlorophyll index (NDCI)—to estimate Chl a concentration in Lake Chad. We evaluated the performance and applicability of Landsat-8 (L8) and Sentinel-2 (S2) images with the four Chl a estimation algorithms. For accuracy, we compared the concentration levels from the four algorithms to those from Worldview-3 (WV3) images. We identified two promising algorithms that could be used alongside L8 and S2 satellite images to monitor Chl a concentrations in Lake Chad. With an averaged R2 of 0.8, the 3BDA and NDCI Chl a algorithms performed accurately with S2 and L8 images. For the S2 and L8 images, 3BDA had the highest performance when compared to the WV3 estimates. We demonstrate the usefulness of sensor images in improving water quality information for areas that are difficult to access or when conventional data are limited.