Polarized CD163+ tumor-associated macrophages are associated with increased angiogenesis and CXCL12 expression in gastric cancer.

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Abstract

Tumor-associated macrophages (TAMs) play a significant role in tumor progression and angiogenesis. However, the prognostic value of TAMs in different histologic locations of gastric cancer (GC) is still unknown. We evaluated the distribution of TAMs in different histologic locations to investigate its importance in predicting prognosis and the relationship with angiogenesis and CXCL12 expression in GC.

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Journal

Journal ID (iso-abbrev): Clin Res Hepatol Gastroenterol

Title: Clinics and research in hepatology and gastroenterology

Publisher: Elsevier BV

ISSN (Electronic): 2210-741X

ISSN (Print): 2210-7401

Publication date (Electronic): Jun 2016

Volume: 40

Issue: 3

Affiliations

[1 ] Department of Pathology, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Republic of Korea.

[2 ] Department of Pathology, Kyung Hee University Hospital, Seoul, Republic of Korea.

[3 ] Department of Pathology, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea.

[4 ] Department of Pathology, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea. Electronic address: sungjig@khu.ac.kr.

Article

Publisher Item ID: S2210-7401(15)00248-X

DOI: 10.1016/j.clinre.2015.09.005

PubMed ID: 26508473

SO-VID: 004c2284-da60-480a-b2fb-8bf630b69125

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