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      Role of microRNAs in drug-resistant ovarian cancer cells.

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          Abstract

          Chemotherapy is the preferred therapeutic approach for the therapy of advanced ovarian cancer, but a successful long-term treatment is prevented by the development of drug resistance. Recent works have underlined the involvement of non-coding RNAs, microRNAs (miRNAs) in cancer development, with several conjectures regarding their possible involvement in the evolution of drug resistance. This work was aimed to identify selected microRNAs involved in the development of chemoresistance in ovarian cancer.

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          Author and article information

          Journal
          Gynecol Oncol
          Gynecologic oncology
          Elsevier BV
          1095-6859
          0090-8258
          Dec 2008
          : 111
          : 3
          Affiliations
          [1 ] Department of Hematology, Istituto Superiore di Sanità, Rome, Italy. antonio.sorrentino@iss.it
          Article
          S0090-8258(08)00645-8
          10.1016/j.ygyno.2008.08.017
          18823650
          00a61d88-aafb-4843-a563-ca01326b9972
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