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Heterogeneous Flare in Prostate-specific Membrane Antigen Positron Emission Tomography Tracer Uptake with Initiation of Androgen Pathway Blockade in Metastatic Prostate Cancer
Rahul Aggarwal ,
Xiao Wei ,
Won Kim ,
Eric J. Small ,
Charles J. Ryan ,
Peter Carroll ,
Matthew Cooperberg ,
Michael J. Evans ,
Thomas Hope
May 2018
May 2018
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Abstract
Prostate-specific membrane antigen (PSMA)-based positron emission tomography (PET)
imaging is a highly sensitive tool for the detection of prostate cancer metastases.
However, the effect of primary and secondary androgen deprivation therapy (ADT) on
PSMA PET uptake has not been described.