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      Non-invasive markers for early diagnosis and determination of the severity of necrotizing enterocolitis.

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          Abstract

          To improve diagnosis of necrotizing enterocolitis (NEC) by noninvasive markers representing gut wall integrity loss (I-FABP and claudin-3) and gut wall inflammation (calprotectin). Furthermore, the usefulness of I-FABP to predict NEC severity and to screen for NEC was evaluated.

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          Author and article information

          Journal
          Ann Surg
          Annals of surgery
          Ovid Technologies (Wolters Kluwer Health)
          1528-1140
          0003-4932
          Jun 2010
          : 251
          : 6
          Affiliations
          [1 ] Department of Surgery, Maastricht University Medical Centre, and Nutrition and Toxicology Research Institute (NUTRIM), Maastricht, The Netherlands.
          Article
          10.1097/SLA.0b013e3181d778c4
          20485148
          03bb3f96-604c-4baa-97df-d6789260b283
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