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      Diarylpentanol constituents from the aerial part of Stelleropsis tianschanica.

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          Abstract

          Five diarylpentanol derivatives including two new compounds stellerasme A (1), stellerasme B (2) were isolated from the aerial parts of Stelleropsis tianschanica. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, CD, 1D and 2D NMR). All compounds were evaluated for their cytotoxicity activity against HeLa and KB cell lines, and compound 1 showed selective activities against HeLa cell line with an IC50 value of 7.4 μM.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): J Asian Nat Prod Res
          Title: Journal of Asian natural products research
          Publisher: Informa UK Limited
          ISSN (Electronic): 1477-2213
          ISSN (Print): 1028-6020
          Publication date (Electronic): Sep 2016
          Volume: 18
          Issue: 9
          Affiliations
          [1 ] a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development , Beijing 100193 , China.
          [2 ] b Department of Natural Medicinal Chemistry , Xinjiang Institute of Chinese and Ethnic Medicine , Urumqi 830002 , China.
          [3 ] d School of Pharmaceutical Sciences , Xiamen University , Xiamen 361102 , China.
          [4 ] c College of Chinese Medicinal Material , Jilin Agricultural University , Changchun 130118 , China.
          Article
          DOI: 10.1080/10286020.2016.1171759
          PubMed ID: 27170544
          SO-VID: 08d80d6c-59ff-4539-ac70-1a01fdf8a3da
          History

          Keywords: Stelleropsis tianschanica,Thymelaeaceae,cytotoxic activity,diarylpentanol derivatives
          Data availability:
          Keywords: Stelleropsis tianschanica, Thymelaeaceae, cytotoxic activity, diarylpentanol derivatives

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