5
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Silicon-Based Sensors for Biomedical Applications: A Review

      review-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The paper highlights some of the significant works done in the field of medical and biomedical sensing using silicon-based technology. The use of silicon sensors is one of the pivotal and prolonged techniques employed in a range of healthcare, industrial and environmental applications by virtue of its distinct advantages over other counterparts in Microelectromechanical systems (MEMS) technology. Among them, the sensors for biomedical applications are one of the most significant ones, which not only assist in improving the quality of human life but also help in the field of microfabrication by imparting knowledge about how to develop enhanced multifunctional sensing prototypes. The paper emphasises the use of silicon, in different forms, to fabricate electrodes and substrates for the sensors that are to be used for biomedical sensing. The electrical conductivity and the mechanical flexibility of silicon vary to a large extent depending on its use in developing prototypes. The article also explains some of the bottlenecks that need to be dealt with in the current scenario, along with some possible remedies. Finally, a brief market survey is given to estimate a probable increase in the usage of silicon in developing a variety of biomedical prototypes in the upcoming years.

          Related collections

          Most cited references98

          • Record: found
          • Abstract: not found
          • Article: not found

          Piezoresistance Effect in Germanium and Silicon

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Bioresorbable pressure sensors protected with thermally grown silicon dioxide for the monitoring of chronic diseases and healing processes

            Pressures in the intracranial, intraocular and intravascular spaces are clinically useful for the diagnosis and management of traumatic brain injury, glaucoma and hypertension, respectively. Conventional devices for measuring these pressures require surgical extraction after a relevant operational time frame. Bioresorbable sensors, by contrast, eliminate this requirement, thereby minimizing the risk of infection, decreasing the costs of care and reducing distress and pain for the patient. However, the operational lifetimes of bioresorbable pressure sensors available at present fall short of many clinical needs. Here, we present materials, device structures and fabrication procedures for bioresorbable pressure sensors with lifetimes exceeding those of previous reports by at least tenfold. We demonstrate measurement accuracies that compare favourably to those of the most sophisticated clinical standards for non-resorbable devices by monitoring intracranial pressures in rats for 25 days. Assessments of the biodistribution of the constituent materials, complete blood counts, blood chemistry and magnetic resonance imaging compatibility confirm the biodegradability and clinical utility of the device. Our findings establish routes for the design and fabrication of bioresorbable pressure monitors that meet requirements for clinical use.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Silicon nanowire field-effect transistor-based biosensors for biomedical diagnosis and cellular recording investigation

                Bookmark

                Author and article information

                Journal
                Sensors (Basel)
                Sensors (Basel)
                sensors
                Sensors (Basel, Switzerland)
                MDPI
                1424-8220
                01 July 2019
                July 2019
                : 19
                : 13
                : 2908
                Affiliations
                [1 ]School of Electronic Engineering, Dongguan University of Technology, Dongguan 523808, China
                [2 ]CSIR-Central Mechanical Engineering Research Institute, Durgapur, West Bengal 713209, India
                [3 ]DGUT-CNAM Institute, Dongguan University of Technology, Dongguan 523106, China
                [4 ]School of Engineering, Macquarie University, Sydney 2109, Australia
                Author notes
                [* ]Correspondence: anindya1991@ 123456gmail.com
                Author information
                https://orcid.org/0000-0002-8422-9288
                Article
                sensors-19-02908
                10.3390/s19132908
                6651638
                31266148
                09dce552-a3db-4a21-970a-acd84f8cd57b
                © 2019 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 10 June 2019
                : 27 June 2019
                Categories
                Review

                Biomedical engineering
                silicon,sensors,biomedical,semiconducting,nanowire
                Biomedical engineering
                silicon, sensors, biomedical, semiconducting, nanowire

                Comments

                Comment on this article