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      Diagnosis and treatment of phrenic nerve hourglass constriction in patients with Parsonage-Turner syndrome

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          Abstract

          Phrenic nerve injury can occur anywhere along its course and clinically results in diaphragm paralysis. Although most patients with Parsonage-Turner syndrome and phrenic nerve dysfunction improve without treatment, some patients do not recover spontaneously. In these cases, an initial autoimmune response produces scarring along the affected nerve(s). This scar, known as an hourglass constriction, causes focal compression of the nerve at the site of the scar, which prevents the nerve from spontaneously recovering. Thus, the authors present a unique case of phrenic nerve injury secondary to Parsonage-Turner syndrome that improved with internal neurolysis.

          The video can be found here: https://stream.cadmore.media/r10.3171/2022.10.FOCVID22105

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          Most cited references7

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          MRI bullseye sign: An indicator of peripheral nerve constriction in parsonage-turner syndrome

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            Neuralgic amyotrophy.

            This review focuses on the current insights and developments in neuralgic amyotrophy (NA), an auto-immune multifocal peripheral nervous system disorder that leaves many patients permanently impaired if not recognized and treated properly.
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              Surgical anatomy of the diaphragm and the phrenic nerve.

              S Fell (1998)
              In this article, the anatomy of the diaphragm and phrenic nerves is discussed, together with related surgical implications. Since the major cause of phrenic nerve injury is surgery, usually for congenital or acquired heart disease, incisions in the diaphragm that do not injure major branches of the phrenic nerve are also discussed. Diaphragmatic plication is usually required in infants less than 3 months of age, and older children may be managed by ventilatory support if electrophysiologic studies document the possibility of return of nerve function. In adults with normal pulmonary function, unilateral diaphragmatic paralysis is usually asymptomatic.
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                Author and article information

                Journal
                Neurosurg Focus Video
                Neurosurg Focus Video
                Neurosurg Focus Video
                Neurosurgical Focus: Video
                American Association of Neurological Surgeons
                2643-5217
                January 2023
                1 January 2023
                : 8
                : 1 , Regaining Function via Peripheral Nerve Surgery
                : V7
                Affiliations
                [1 ]Department of Neurological Surgery, Columbia University Irving Medical Center, New York;
                [2 ]Department of Rehabilitation and Regenerative Medicine, Columbia University College of Physicians and Surgeons, New York;
                [3 ]Department of Thoracic Surgery, Columbia University Irving Medical Center, New York, New York
                Author notes
                Correspondence Travis S. CreveCoeur: Columbia University Irving Medical Center, New York, NY. tc282@ 123456cumc.columbia.edu .

                INCLUDE WHEN CITING DOI: 10.3171/2022.10.FOCVID22105.

                Disclosures Dr. Visco: personal fees from AMSSM, outside the submitted work; and board member of the Association of Academic Physiatry.

                Article
                2022.10.FOCVID22105
                10.3171/2022.10.FOCVID22105
                9815208
                36628100
                0b55b9a4-e23a-46fe-b96d-1d1f3d426db6
                © 2023, The Authors

                This is an open access article distributed under the CC BY license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 01 September 2022
                : 03 October 2022
                Page count
                Figures: 0, Tables: 0, References: 7, Pages: 3
                Categories
                Article

                phrenic nerve,parsonage-turner syndrome,diaphragm paralysis

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