Comparative antiproliferation of human prostate cancer cells by ethanolic extracts of two groups of Brazilian propolis Translated title: Antiproliferação comparativa de células prostáticas humanas por extratos etanólicos de dois grupos de própolis brasileira

Abstract

Two groups of propolis, group 12, which was collected in the southeastern Brazil and group 13, which was collected in the northeastern Brazil, were examined for antiproliferation of primary malignant tumor (RC-58T/h/SA#4)-derived human prostate cancer cells and human prostate epithelial cells. The strongest inhibition of RC-58T/h/SA#4 cells was observed in propolis group 13 extracts, whereas moderate growth inhibition was observed in human prostate epithelial cells in comparison with group 12. It can be said that the Brazilian propolis of group 13 contains important chemical ingredients.

Translated abstract

Própolis de dois grupos, do grupo 12, coletada no sudeste do Brasil, e do grupo 13, coletada no nordeste do Brasil, foram examinadas quanto à antiproliferação de tumor maligno primário (RC-58T/h/SA#4), derivado de células de câncer prostático humano e células epiteliais prostáticas humanas. A inibição mais forte de células RC-58T/h/SA#4 foi observada no extrato de própolis do grupo 13, enquanto que foi observada inibição de crescimento moderada em células epiteliais prostáticas humanas no grupo 12. Conclui-se que a própolis brasileira do grupo 13 contém importantes ingredientes químicos.