Penile's melanoma is a rare situation, often associated with late diagnosis and high morbidity and mortality. We report the case of a 70‐year‐old man. He represented progressive skin lesions of the penile gland. A surgical biopsy with histopathological and immunohistochemical studies established the diagnosis of malignant melanoma of the penis in the metastatic stage. This case was managed by palliative immunotherapy and is currently under treatment by Pembrolizumab. Malignant melanoma of the penis represents an exceptional situation, in which only rapid diagnosis at an early stage allows treatment with optimal therapeutic results.
Penile's melanoma is a serious disease whose diagnosis is often late because of its intimate location. We have to encourage our patients to consult a doctor quickly in the face of any skin lesion of the penis to be taken care of adequately.